Article
Microglia density decreases with age in a mouse model of Huntington's disease.
Glia - 1 Sept 2003
Ma Li, Morton A Jennifer, Nicholson Louise F B
Abstract excerpt
Huntington's disease (HD) is characterized by selective neuronal loss and reactive gliosis. In the R6/2 transgenic HD mouse model, there is no selective cell loss, although astrocytosis has been reported. Since there have been no previous studies on microglia in this model, we have undertaken a d...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
