Article
Transforming growth factor beta-1 and gene polymorphisms in oriental ankylosing spondylitis.
Rheumatology (Oxford, England) - 1 Jan 2005
Howe H S, Cheung P L, Kong K O, Badsha H, Thong B Y H, Leong K P, Koh E T, Lian T Y, Cheng Y K, Lam S, Teo D, Lau T C, Leung B P
Abstract excerpt
OBJECTIVES: To study serum levels of transforming growth factor beta-1 (TGFbeta1) and the expression of TGFbeta1 in in vitro peripheral blood mononuclear cell (PBMC) cultures in oriental ankylosing spondylitis (AS) patients, and to determine their association with codon 10 and 25 TGFB1 gene polymorphisms. METHODS: Serum levels of TGFbeta1 were measured by enzyme-linked immunosorbent assay (ELISA). The ability of...
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