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Article

Interleukin 10 polymorphisms in ankylosing spondylitis.

Genes and immunity - 1 Jan 2003

Goedecke V, Crane A M, Jaakkola E, Kaluza W, Laiho K, Weeks D E, Wilson J, Kauppi M, Kaarela K, Tuomilehto J, Wordsworth B P, Brown M A

Abstract excerpt

Genetic polymorphisms of the IL10 promoter region have been implicated in many autoimmune diseases, including seronegative spondyloarthropathies. We studied three SNPs (IL10-1087, -824, and -597) and two microsatellites (IL10R and IL10G) lying within the promoter region of IL10 for association with susceptibility to and clinical manifestations of ankylosing spondylitis (AS), a common form of spondyloarthritis....

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PMID: 12595905
DOI: 10.1038/sj.gene.6363930

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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