Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Fluorescence detection of single nucleotide polymorphisms using nucleic acid probe containing tricyclic base-linked acyclonucleoside.

Bioorganic & medicinal chemistry letters - 1 Jan 2012

Hattori Mayumi, Ohki Tokimitsu, Yanase Emiko, Ueno Yoshihito

Abstract excerpt

A reliable and simple method for detecting nucleobase mutations is very important clinically because sequence variations in human DNA cause genetic diseases and genetically influenced traits. A majority of sequence variations are attributed to single nucleotide polymorphisms (SNPs). Here, we developed a method for SNP detection using DNA probes that contained a fluorescent tricyclic base-linked acyclonucleoside...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Base Pair Mismatch
Share to Cytochrome P-450 CYP2C9

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Genetic Techniques

Share to Models, Chemical

Share to Nucleic Acids

Share to Nucleosides

Share to Oligodeoxyribonucleotides

Share to Spectrometry, Fluorescence

Source

Identifiers

PMID: 22133629
DOI: 10.1016/j.bmcl.2011.11.022

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Fluorescence detection of single nucleotide polymorphisms using nucleic acid probe containing tricyclic base-linked acyclonucleoside.PMID 22133629Read ↗

Nucleic acid probe containing fluorescent tricyclic base-linked acyclonucleoside for detection of single nucleotide polymorphisms.Semantic proximity Read ↗

Synthesis of a fluorescence resonance energy transfer-based probe containing a tricyclic nucleoside analog for single nucleotide polymorphism typing.Semantic proximity Read ↗

Fluorescent detection of single nucleotide polymorphism utilizing a hairpin DNA containing a nucleotide base analog pyrrolo-deoxycytidine as a fluorescent probe.Semantic proximity Read ↗

Fluorescence detection of single-nucleotide differences using aptamer-forming binary DNA probes.Semantic proximity Read ↗

Design of base-discriminating fluorescent nucleoside and its application to t/c SNP typing.Semantic proximity Read ↗

Pyrene-labeled base-discriminating fluorescent DNA probes for homogeneous SNP typing.Semantic proximity Read ↗

Anthracene based base-discriminating fluorescent oligonucleotide probes for SNPs typing: synthesis and photophysical properties.Semantic proximity Read ↗

Single-Labeled Oligonucleotides Showing Fluorescence Changes Upon Hybridization with Target Nucleic Acids.Semantic proximity Read ↗

Design of dual-labeled oligonucleotide probes for SNPs genotyping.Semantic proximity Read ↗

Fluorescence detection of single-nucleotide polymorphisms with two simple and low cost methods: a double-DNA-probe method and a bulge form method.Semantic proximity Read ↗

Homogeneous and label-free fluorescence detection of single-nucleotide polymorphism using target-primed branched rolling circle amplification.Semantic proximity Read ↗

Fluorescence and visual detection of single nucleotide polymorphism using cationic conjugated polyelectrolyte.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.