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Article

Nucleic acid probe containing fluorescent tricyclic base-linked acyclonucleoside for detection of single nucleotide polymorphisms.

Bioorganic & medicinal chemistry - 1 Jan 2012

Furukawa Kinji, Hattori Mayumi, Ohki Tokimitsu, Kitamura Yoshiaki, Kitade Yukio, Ueno Yoshihito

Abstract excerpt

The development of a reliable and simple method for detecting single nucleotide polymorphisms (SNPs), common genetic variations in the human genome, is currently an important research area because SNPs are important for identifying disease-causing genes and for pharmacogenetic studies. Here, we developed a novel method for SNP detection. We designed and synthesized DNA probes containing a fluorescent tricyclic...

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PMID: 22177406
DOI: 10.1016/j.bmc.2011.11.045

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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