Article
In vivo roles of Rad52, Rad54, and Rad55 proteins in Rad51-mediated recombination.
Molecular cell - 1 Jul 2003
Sugawara Neal, Wang Xuan, Haber James E
Abstract excerpt
Repairing a double-strand break by homologous recombination requires binding of the strand exchange protein Rad51p to ssDNA, followed by synapsis with a homologous donor. Here we used chromatin immunoprecipitation to monitor the in vivo association of Saccharomyces cerevisiae Rad51p with both the cleaved MATa locus and the HML alpha donor. Localization of Rad51p to MAT precedes its association with HML, providing...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.