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Article

Identification of epistatic interaction involved in obesity using the KK/Ta mouse as a Type 2 diabetes model: is Zn-alpha2 glycoprotein-1 a candidate gene for obesity?

Diabetes - 1 Aug 2003

Gohda Tomohito, Makita Yuichiro, Shike Toshihide, Tanimoto Mitsuo, Funabiki Kazuhiko, Horikoshi Satoshi, Tomino Yasuhiko

Abstract excerpt

The KK/Ta strain serves as a suitable polygenic mouse model for the common form of type 2 diabetes associated with obesity in humans. Recently, we reported the susceptibility loci contributing to type 2 diabetes and related phenotypes in KK/Ta mice. In this study, we focused on expression in the kidneys and liver of KK/Ta and BALB/c mice using differential display (DD) PCR. Zn-alpha(2) glycoprotein-1 (Azgp1) mRNA...

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Identifiers

PMID: 12882938
DOI: 10.2337/diabetes.52.8.2175

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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