Article
M-cadherin, a candidate gene for type 2 diabetes and related phenotypes in a KK/Ta mouse model.
Acta diabetologica - 1 Mar 2007
Shiina K, Gohda T, Murakoshi M, Yamada K, Aoki T, Yamazaki T, Tanimoto M, Tomino Y
Abstract excerpt
The KK/Ta strain serves as a suitable polygenic mouse model for type 2 diabetes associated with fasting hyperglycaemia, glucose intolerance, hyperinsulinaemia, mild obesity and dyslipidaemia. Recently, we reported the susceptibility loci contributing to type 2 diabetes and related phenotypes in KK/Ta mice. In the present study, to identify susceptibility genes for type 2 diabetes and related disorders, GeneChip...
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