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Article

Transcriptional outputs of the Caenorhabditis elegans forkhead protein DAF-16.

Aging cell - 1 Apr 2003

McElwee Joshua, Bubb Kerry, Thomas James H

Abstract excerpt

In Caenorhabditis elegans, the forkhead protein DAF-16 transduces insulin-like signals that regulate larval development and adult lifespan. To identify DAF-16-dependent transcriptional alterations that occur in a long-lived C. elegans strain, we used cDNA microarrays and genomic analysis to identify putative direct and indirect DAF-16 transcriptional target genes. Our analysis suggests that DAF-16 action...

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Identifiers

PMID: 12882324
DOI: 10.1046/j.1474-9728.2003.00043.x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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