Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Adenosine slows migration of dendritic cells but does not affect other aspects of dendritic cell maturation.

The Journal of investigative dermatology - 1 Aug 2003

Hofer Susanne, Ivarsson Lennart, Stoitzner Patrizia, Auffinger Margit, Rainer Christian, Romani Nikolaus, Heufler Christine

Abstract excerpt

We report the induction and reduction of adenosine receptor A2a and A3 mRNAs, respectively, during maturation of human monocyte-derived dendritic cells. Adenosine, an immunomodulatory molecule, is unstable in vitro; therefore we tested a stable agonist, 5'-(N-ethylcarboxamido)-adenosine, to explo...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Adenosine
Share to Cellular Senescence
Share to Chemokines, CC

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Culture Techniques

Share to Dendritic Cells

Share to Langerhans Cells

Share to Lymph Nodes

Source

Identifiers

PMID: 12880422
DOI: 10.1046/j.1523-1747.2003.12369.x

Genes

CCL19
MIP
CCR5

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026. Prepared record publication-12880422-2026-09-01.1. Manifest publication-graph-cohort-2026-09-01.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 1 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Adenosine slows migration of dendritic cells but does not affect other aspects of dendritic cell maturation.PMID 12880422Read ↗

Adenosine and cAMP signalling skew human dendritic cell differentiation towards a tolerogenic phenotype with defective CD8(+) T-cell priming capacity.Semantic proximity Read ↗

Human dendritic cells differentiated in hypoxia down-modulate antigen uptake and change their chemokine expression profile.Semantic proximity Read ↗

Adenosine Receptor Signaling Targets Both PKA and Epac Pathways to Polarize Dendritic Cells to a Suppressive Phenotype.Semantic proximity Read ↗

Dual blockade of adenosine A2A and A 2B receptors is required to reverse NECA-induced immunosuppression in human macrophages: Implications for cancer immunotherapySemantic proximity Read ↗

HIF-dependent induction of adenosine receptor A2b skews human dendritic cells to a Th2-stimulating phenotype under hypoxia.Semantic proximity Read ↗

Mycophenolic acid impedes the antigen presenting and lymph node homing capacities of human blood myeloid dendritic cells.Semantic proximity Read ↗

Dendritic cells phenotype fitting under hypoxia or lipopolysaccharide; adenosine 5'-triphosphate-binding cassette transporters far beyond an efflux pump.Semantic proximity Read ↗

Hypoxia inhibits the migratory capacity of human monocyte-derived dendritic cells.Semantic proximity Read ↗

Conditioned medium from HeLa cells enhances motility of human monocyte-derived dendritic cells but abrogates their maturation and endocytic activity.Semantic proximity Read ↗

Both dendritic cells and memory T lymphocytes emigrate from organ cultures of human skin and form distinctive dendritic-T-cell conjugates.Semantic proximity Read ↗

Maturation of human dendritic cells as sulfasalazine target.Semantic proximity Read ↗

CNI-1493 mediated suppression of dendritic cell activation in vitro and in vivo.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.