Article
The Leishmania tarentolae spliced leader contains determinants for association with polysomes.
The Journal of biological chemistry - 3 Oct 2003
Zeiner Gusti M, Sturm Nancy R, Campbell David A
Abstract excerpt
In kinetoplastids, every nuclear-derived mRNA contains an identical 39-nucleotide (nt) spliced leader at its 5'-terminus. The spliced leader is derived from substrate spliced leader RNA and joined to pre-mRNA by trans-splicing, thus providing mature mRNAs with an m7G cap and additional methylations referred to as cap 4. It was shown previously that mutations spanning nucleotides 10-39 of the spliced leader did...
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