Efficient trans-splicing of mutated spliced leader exons in Leishmania tarentolae.

doi:10.1074/jbc.273.30.18689

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Article

Efficient trans-splicing of mutated spliced leader exons in Leishmania tarentolae.

The Journal of biological chemistry - 24 Jul 1998

Sturm N R, Fleischmann J, Campbell D A

Abstract excerpt

Every kinetoplastid mRNA receives a common, conserved leader sequence via the process of trans-splicing. In Leishmania tarentolae the precursor spliced leader RNA is 96 nucleotides, with a 39-nucleotide exon that is 7meG-capped and methylated on the first 4 nucleotides. trans-Splicing was inferre...

Topics

Alternative Splicing
Animals
Base Sequence
Exons
Introns
Leishmania
Molecular Sequence Data
Mutagenesis, Site-Directed
Phenotype
Protein Sorting Signals
RNA, Messenger
Structure-Activity Relationship

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