Article
Multiple requirements for nematode spliced leader RNP function in trans-splicing.
RNA (New York, N.Y.) - 1 Aug 1996
Denker J A, Maroney P A, Yu Y T, Kanost R A, Nilsen T W
Abstract excerpt
The 5' exon donor in nematode trans-splicing, the SL RNA, is a small (approximately 100 nt) RNA that resembles cis-spliceosomal U snRNAs. Extensive analyses of the RNA sequence requirements for SL RNA function have revealed four essential elements, the core Sm binding site, three nucleotides immediately downstream of this site, a region of Stem-loop II, and a 5' splice site. Although these elements are necessary...
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