Article
Trypanosome spliced-leader-associated RNA (SLA1) localization and implications for spliced-leader RNA biogenesis.
Eukaryotic cell - 1 Jan 2009
Hury Avraham, Goldshmidt Hanoch, Tkacz Itai Dov, Michaeli Shulamit
Abstract excerpt
Spliced-leader-associated RNA (SLA1) guides the pseudouridylation at position -12 (relative to the 5' splice site) of the spliced-leader (SL) RNA in all trypanosomatid species. Nevertheless, the exact role of this RNA is currently unknown. Here, we demonstrate that the absence of pseudouridine on Leptomonas collosoma SL RNA has only a minor effect on the ability of this RNA to function in trans splicing in vivo....
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
