Article
[Association between interleukin-1 composite genotype and severe periodontitis: case-control study].
Minerva stomatologica - 1 Jun 2003
Nastri L, Caruso F
Abstract excerpt
AIM: Interleukin-1 (IL-1) is a bone resorption stimulating cytokine that is implicated in the development of periodondal lesions. Recent studies suggest that the production of this mediator depends for quantity on a specific allelic combination in its genetic cluster. Periodontitis severity was correlated with the extent of the form 2 allele at the position -889 in the gene IL-1A, together with the form 2 allele...
Topics
- Adult
- Aged
- Alleles
- Bone Resorption
- Case-Control Studies
- Female
- Gene Frequency
- Genetic Predisposition to Disease
- Genotype
- Gingival Hemorrhage
- Humans
- Interleukin-1