Article
The association of the composite IL-1 genotype with periodontitis progression and/or treatment outcomes: a systematic review.
Journal of clinical periodontology - 1 Apr 2007
Huynh-Ba G, Lang N P, Tonetti M S, Salvi G E
Abstract excerpt
BACKGROUND: Genetically transmitted traits such as cytokine gene polymorphisms may accentuate the host inflammatory response to the bacterial challenge and influence susceptibility to periodontitis. OBJECTIVE: To systematically review the evidence of an association between the interleukin-1 (IL-1) composite genotype, i.e. presence of the allele 2 in the gene clusters IL-1A-889 and in IL-1B +3953, and...
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