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Article

Association between interleukin-1 gene polymorphism and severity of chronic periodontitis in a south Indian population group

1 Jan 2012

Abstract excerpt

BACKGROUND: Periodontitis is a bacterial disease modified by multiple factors. Interleukin-1 (IL-1) is a key regulator of the host response and a major modulator of extracellular matrix catabolism and bone resorption. It has been reported that variations in IL-1 gene are associated with increased susceptibility to periodontitis. The aims of the study were 1) to analyze the distribution of single nucleotide...

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PMID: 23055581
DOI: 10.4103/0972-124x.99258

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