Article
Assessment of single nucleotide polymorphism at IL-1A+4845 and IL-1B+3954 as genetic susceptibility test for chronic periodontitis in Maharashtrian ethnicity.
Journal of periodontology - 1 Sept 2006
Agrawal Amit A, Kapley Atya, Yeltiwar Ramreddy K, Purohit Hemant J
Abstract excerpt
BACKGROUND: The inflammatory response that is directed in large part by proinflammatory cytokine interleukin (IL)-1 is genetically determined, with some people having a more vigorous response than others to the same stimulus. The reason for this is speculated that the dysregulated production of I...
Topics
- Alleles
- Case-Control Studies
- Chi-Square Distribution
- Chronic Disease
- Female
- Gene Frequency
- Genetic Predisposition to Disease
- Genotype
- Humans
- India
- Interleukin-1
- Male
- Molecular Epidemiology
- Odds Ratio
- Periodontal Attachment Loss
- Periodontal Index
- Periodontitis
- Polymorphism, Restriction Fragment Length