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Article

Patched 1 conditional null allele in mice.

Genesis (New York, N.Y. : 2000) - 1 Jul 2003

Ellis Tammy, Smyth Ian, Riley Emily, Graham Scott, Elliot Kate, Narang Monica, Kay Graham F, Wicking Carol, Wainwright Brandon

Abstract excerpt

The patched gene (Ptc) is a member of the hedgehog signaling pathway which plays a central role in the development of many invertebrate and vertebrate tissues. In addition, Ptc and a number of other pathway members are mutated in some common human cancers. Patched is the receptor for the hedgehog...

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Source

Identifiers

PMID: 12872247
DOI: 10.1002/gene.10208

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026. Prepared record publication-12872247-2026-09-01.1. Manifest publication-graph-cohort-2026-09-01.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 1 Sept 2026.

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