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Article

Defects in mouse mammary gland development caused by conditional haploinsufficiency of Patched-1.

Development (Cambridge, England) - 1 Nov 1999

Lewis M T, Ross S, Strickland P A, Sugnet C W, Jimenez E, Scott M P, Daniel C W

Abstract excerpt

In vertebrates, the hedgehog family of cell signaling proteins and associated downstream network components play an essential role in mediating tissue interactions during development and organogenesis. Loss-of-function or misexpression mutation of hedgehog network components can cause birth defects, skin cancer and other tumors. The mammary gland is a specialized skin derivative requiring epithelial-epithelial...

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Identifiers

PMID: 10529434
DOI: 10.1242/dev.126.22.5181

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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Defects in mouse mammary gland development caused by conditional haploinsufficiency of Patched-1.PMID 10529434Read ↗

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