Article
Association of a promoter variant of the haeme oxygenase-1 gene with hypertension in women.
Journal of hypertension - 1 Aug 2003
Ono Koh, Mannami Toshifumi, Iwai Naoharu
Abstract excerpt
OBJECTIVE: To examine the relationship between the gene for haeme oxygenase (HO)-1 (HMOX-1) and human essential hypertension, because both the acute and systemic induction of HMOX-1 have been suggested to attenuate vascular tone and blood pressure. METHODS: We screened for sequence variations in HMOX-1 and conducted an association study, using these polymorphisms, in a large cohort (1998 individuals) representing...
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