Article
Cell-cell interactions prevent a potential inductive interaction between soma and germline in C. elegans.
Cell - 15 Jun 1990
Seydoux G, Schedl T, Greenwald I
Abstract excerpt
In each gonadal arm of wild-type C. elegans hermaphrodites, the somatic distal tip cell (DTC) maintains distal germline nuclei in mitosis, while proximal nuclei enter meiosis. We have identified two conditions under which a proximal somatic cell, the anchor cell (AC), inappropriately maintains proximal germline nuclei in mitosis: when defined somatic gonadal cells have been ablated in wild type, and in lin-12...
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