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Article

Cell-cell interactions prevent a potential inductive interaction between soma and germline in C. elegans.

Cell - 15 Jun 1990

Seydoux G, Schedl T, Greenwald I

Abstract excerpt

In each gonadal arm of wild-type C. elegans hermaphrodites, the somatic distal tip cell (DTC) maintains distal germline nuclei in mitosis, while proximal nuclei enter meiosis. We have identified two conditions under which a proximal somatic cell, the anchor cell (AC), inappropriately maintains proximal germline nuclei in mitosis: when defined somatic gonadal cells have been ablated in wild type, and in lin-12...

Topics

Animals
Caenorhabditis
Cell Communication
Disorders of Sex Development
Germ Cells
Mitosis
Models, Genetic
Mosaicism
Mutation
Phenotype

Source

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 2350786
DOI: 10.1016/0092-8674(90)90060-r

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-2350786-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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