Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

A novel developmental mechanism in Dictyostelium revealed in a screen for communication mutants.

Developmental biology - 15 Jul 2003

Kibler Kirsten, Nguyen Tu-Lan, Svetz Jessica, Van Driessche Nancy, Ibarra Miroslava, Thompson Christopher, Shaw Chad, Shaulsky Gad

Abstract excerpt

We performed a screen for signaling genes by selecting mutant strains of Dictyostelium that fail to develop spores in a pure population but sporulate well in chimerae with wild type cells. We found 9 strains whose sporulation was induced up to 10 million-fold in chimerae. Most strains were also able to sporulate in chimerae with each other, but 2 pairs failed to do so, suggesting that the genes in each pair...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cell Communication
Share to Chimera

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Dictyostelium

Share to Gene Expression Regulation, Developmental

Share to Genes, Protozoan

Share to Mutagenesis, Insertional

Share to Protozoan Proteins

Share to Recombinant Proteins

Source

Identifiers

PMID: 12871696
DOI: 10.1016/s0012-1606(03)00204-5

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

A novel developmental mechanism in Dictyostelium revealed in a screen for communication mutants.PMID 12871696Read ↗

Cheating by exploitation of developmental prestalk patterning in Dictyostelium discoideum.Semantic proximity Read ↗

Mef2A, a homologue of animal Mef2 transcription factors, regulates cell differentiation in Dictyostelium discoideum.Semantic proximity Read ↗

A set of genes conserved in sequence and expression traces back the establishment of multicellularity in social amoebae.Semantic proximity Read ↗

Assessment of development and chemotaxis in Dictyostelium discoideum mutants.Semantic proximity Read ↗

Loss of Copine D Leads to Ras Activation in Dictyostelium discoideum.Semantic proximity Read ↗

A novel Dictyostelium RasGEF required for chemotaxis and development.Semantic proximity Read ↗

The Dictyostelium genome encodes numerous RasGEFs with multiple biological roles.Semantic proximity Read ↗

Activated cAMP receptors switch encystation into sporulation.Semantic proximity Read ↗

ABC transporters in Dictyostelium discoideum development.Semantic proximity Read ↗

Loss of Copine D Leads to Ras Activation in <i>Dictyostelium discoideum</i>Semantic proximity Read ↗

Mutual suppression between mutations in the Dictyostelium Greenbeard pathway restores wild-type development.Semantic proximity Read ↗

Reverse genetic analyses of gamete-enriched genes revealed a novel regulator of the cAMP signaling pathway in Dictyostelium discoideum.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.