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Article

A set of genes conserved in sequence and expression traces back the establishment of multicellularity in social amoebae.

BMC genomics - 4 Nov 2016

Schilde Christina, Lawal Hajara M, Noegel Angelika A, Eichinger Ludwig, Schaap Pauline, Glöckner Gernot

Abstract excerpt

BACKGROUND: The developmental cycle of Dictyostelid amoebae represents an early form of multicellularity with cell type differentiation. Mutant studies in the model Dictyostelium discoideum revealed that its developmental program integrates the actions of genes involved in signal transduction, adhesion, motility, autophagy and cell wall and matrix biosynthesis. However, due to functional redundancy and fail safe...

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Identifiers

PMID: 27814692
DOI: 10.1186/s12864-016-3223-z
PMCID: PMC5097433

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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