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Article

Analysis of p16 gene mutations and deletions in childhood acute lymphoblastic leukemias.

Sao Paulo medical journal = Revista paulista de medicina - 5 Mar 2003

Lemos Jos Alexandre Rodrigues, Defavery Ricardo, Scrideli Carlos Alberto, Tone Luiz Gonzaga

Abstract excerpt

CONTEXT: The p16 tumor suppressor gene encodes a cyclin-dependent kinase 4 inhibitor that blocks cell division during the G1 phase of the cell cycle. Alterations in this gene have been reported for various neoplasia types, including acute lymphoblastic leukemias (ALL), especially T-cell acute lymphoblastic leukemias (ALL). OBJECTIVE: To determine probable alterations in the p16 gene in children with acute...

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Source

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Identifiers

PMID: 12870051
DOI: 10.1590/s1516-31802003000200005
PMCID: PMC11108625

Genes

EFS

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Analysis of p16 gene mutations and deletions in childhood acute lymphoblastic leukemias.PMID 12870051Read ↗

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