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Article

Type III Cu mutants of Myrothecium verrucaria bilirubin oxidase.

Journal of biochemistry - 1 Jun 2003

Shimizu Atsushi, Samejima Tatsuya, Hirota Shun, Yamaguchi Shotaro, Sakurai Nobuhiko, Sakurai Takeshi

Abstract excerpt

Type III Cu ligand, His456 and His458, of Myrothecium verrucaria (MT-1) bilirubin oxidases (BO) [EC 1.3.3.5] were doubly mutated as to Lys, Asp, and Val. In spite of perturbation of the type III Cu centers, these mutants were pale blue or colourless when isolated. However, they became intense blue on reaction with reducing agents such as dithionite, ascorbate, hexacyanoferrate(II), and octacyanotangstate(IV)...

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PMID: 12869533
DOI: 10.1093/jb/mvg098

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

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