Article
Compensatory binding of an asparagine residue to the coordination-unsaturated type I Cu center in bilirubin oxidase mutants.
Biochemical and biophysical research communications - 4 Jul 2008
Kataoka Kunishige, Tsukamoto Keishi, Kitagawa Rieko, Ito Takahiro, Sakurai Takeshi
Abstract excerpt
Met467, the axial ligand to type I Cu in a multicopper oxidase, Myrothecium verrucaria bilirubin oxidase was substituted with a non-coordinating Phe and Leu to transform the spectral and magnetic properties and oxidase activities of the enzyme into those of fungal laccases, but the mutated type I...
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