Article
The kinetic role of carboxylate residues in the proximity of the trinuclear centre in the O2 reactivity of CotA-laccase.
Dalton transactions (Cambridge, England : 2003) - 28 May 2012
Brissos Vânia, Chen Zhenjia, Martins Lígia O
Abstract excerpt
Multicopper oxidases catalyze the four-electron reduction of dioxygen to water without the release of any reactive oxygen intermediate species. The role of carboxylate residue Asp116 located at the exit channel for water molecules of CotA-laccase has been investigated by site-saturation mutagenes...
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