Expression Profile of a γ-Deletion Variant of the Human Telomerase Reverse Transcriptase Gene

Abstract excerpt

The human telomerase reverse transcriptase (hTERT) is an essential component of the holoenzyme complex that adds telomeric repeats to the ends of chromosomes. The hTERT transcript has been shown to have two deletion type alternative splicing sites. One deletion site induces the alpha-deletion variant, lacking 36 bp from exon 6, and the other induces the beta-deletion variant, lacking 182 bp from exons 7 and 8....

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• Share to Advanced biosensing and bioanalysis techniques
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