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Article

Exclusion of Exon 2 Is a Common mRNA Splice Variant of Primate Telomerase Reverse Transcriptases

24 Oct 2012

Abstract excerpt

Telomeric sequences are added by an enzyme called telomerase that is made of two components: a catalytic protein called telomerase reverse transcriptase (TERT) and an integral RNA template (TR). Telomerase expression is tightly regulated at each step of gene expression, including alternative splicing of TERT mRNA. While over a dozen different alternative splicing events have been reported for human TERT mRNA,...

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Share to Advanced biosensing and bioanalysis techniques
Share to RNA Interference and Gene Delivery
Share to Telomeres, Telomerase, and Senescence

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PMID: 23110161
DOI: 10.1371/journal.pone.0048016

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