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Article

Choline, Other Methyl-Donors and Epigenetics.

Nutrients - 29 Apr 2017

Zeisel Steven

Abstract excerpt

Choline dietary intake varies such that many people do not achieve adequate intakes. Diet intake of choline can modulate methylation because, via betaine homocysteine methyltransferase (BHMT), this nutrient (and its metabolite, betaine) regulate the concentrations of S-adenosylhomocysteine and S-adenosylmethionine. Some of the epigenetic mechanisms that modify gene expression without modifying the genetic code...

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Identifiers

PMID: 28468239
DOI: 10.3390/nu9050445
PMCID: PMC5452175

Genes

BHMT

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

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