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Article

Mu-opioid receptor desensitization: role of receptor phosphorylation, internalization, and representation.

The Journal of biological chemistry - 19 Sept 2003

Qiu Yu, Law Ping-Yee, Loh Horace H

Abstract excerpt

It is generally accepted that the internalization and desensitization of mu-opioid receptor (MOR) involves receptor phosphorylation and beta-arrestin recruitment. However, a mutant MOR, which is truncated after the amino acid residue Ser363 (MOR363D), was found to undergo phosphorylation-independent internalization and desensitization. As expected, MOR363D, missing the putative agonist-induced phosphorylation...

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Source

Identifiers

PMID: 12860981
DOI: 10.1074/jbc.M305857200

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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