Article
Cancer proneness of linear porokeratosis may be explained by allelic loss.
Dermatology (Basel, Switzerland) - 1 Jan 1997
Happle R
Abstract excerpt
BACKGROUND: It is well known that porokeratosis, a genetically heterogeneous disorder characterized by the histopathological feature of the cornoid lamella, shows an increased proneness to develop carcinoma. On the other hand, a significant mechanism in the origin of many forms of cancer is loss of heterozygosity or allelic loss. OBJECTIVE: Because it has recently been proposed that linear porokeratosis may...
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