Article
Oestrogen receptor alpha gene polymorphism is related to aortic valve sclerosis in postmenopausal women.
Journal of internal medicine - 1 Aug 2003
Nordström P, Glader C A, Dahlén G, Birgander L Slunga, Lorentzon R, Waldenström A, Lorentzon M
Abstract excerpt
OBJECTIVES: Aortic valvular sclerosis (AS) is an inflammatory process and not a result of normal ageing. The sclerotic process is accelerated by risk factors such as smoking and high cholesterol levels. The genetic factors for the development of AS are however unknown. Therefore the purpose of the present study was to investigate whether polymorphisms in the oestrogen receptor alpha (ORalpha) gene and in the...
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