Article
The relationship between four single nucleotide polymorphisms in the promoter region of the osteoprotegerin gene and aortic calcification or coronary artery disease in Koreans.
Clinical endocrinology - 1 Jun 2006
Rhee Eun Jung, Oh Ki Won, Jung Chan Hee, Lee Won Young, Oh Eun Sook, Yun Eun Joo, Baek Ki Hyun, Kang Moo Il, Kim Sun Woo
Abstract excerpt
OBJECTIVE: Osteoprotegerin (OPG) is a recently identified cytokine that acts as a decoy receptor for the receptor activator of the NF-kappaB ligand (RANKL). OPG has been shown to be an important inhibitor of osteoclastogenesis and arterial calcification in animal models. OPG has been proposed as...
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