Article
Association between oestrogen receptor alpha gene polymorphism and mortality in female end-stage renal disease patients.
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association - 1 Sept 2007
Kato Sawako, Lindholm Bengt, Axelsson Jonas, Qureshi Rashid A, Barany Peter, Heimbürger Olof, Gustafsson Jan-Ake, Stenvinkel Peter, Nordfors Louise
Abstract excerpt
BACKGROUND: In the general population, genetic variations in the oestrogen receptor alpha (ERalpha) gene may influence lipid abnormalities, cardiovascular disease (CVD), and mortality, but this has not previously been studied in end-stage renal disease (ESRD) patients. METHODS: A total of 227 ESRD (141 men and 86 women) patients starting renal replacement therapy (RRT) were genotyped for three ERalpha gene...
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