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Article

Parathyroid hormone gene variant and calcific aortic stenosis.

The Journal of heart valve disease - 1 May 2009

Schmitz Fabian, Ewering Silke, Zerres Klaus, Klomfass Sebastian, Hoffmann Rainer, Ortlepp Jan R

Abstract excerpt

BACKGROUND AND AIM OF THE STUDY: Calcific aortic stenosis (AS) is the most frequently acquired valvular disease of the elderly in the Western world. A genetic background for AS has been proposed. The deposition of calcium hydroxyapatite is the key problem of valve calcification; vitamin D and parathyroid hormone are major factors in calcium homeostasis. The vitamin D receptor (VDR) gene and parathyroid hormone...

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Source

Identifiers

PMID: 19557980

Genes

PTH
VDR

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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