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Article

Role of IL-10 promoter polymorphisms in the development of severe aorto-iliac occlusive disease.

Human immunology - 1 Oct 2008

Blanco Estrella, Moñux Guillermo, Mas Ana, Serrano Francisco J, de la Concha Emilio G, Urcelay Elena

Abstract excerpt

Aortic severe occlusive disease (ASO) is a peripheral manifestation of atherosclerosis with an inflammatory component. Interleukin (IL)-10 is an anti-inflammatory cytokine that plays a key role in the development of atherosclerosis, promoting the stability of the atherosclerotic plaque. Several polymorphisms within the 5' region of the IL-10 gene have been related to altered transcriptional activity and protein...

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Identifiers

PMID: 18703105
DOI: 10.1016/j.humimm.2008.07.005

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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