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Article

Transformation of Mucor miehei results in plasmid deletion and phenotypic instability.

FEMS microbiology letters - 15 Jul 2003

Monfort Aurelia, Cordero Laura, Maicas Sergi, Polaina Julio

Abstract excerpt

Mucor miehei transformants resistant to geneticin have been obtained by treatment of protoplasts with different plasmids and by Agrobacterium-mediated DNA transfer. All transformants exhibited a very unstable phenotype whose maintenance required continuous selective pressure. Molecular analysis of transformants showed that the plasmid DNA was extensively modified and maintained in very low amount. Our results...

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Identifiers

PMID: 12855175
DOI: 10.1016/S0378-1097(03)00421-X

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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