Instability of the mutated biotin operon plasmid in a biotin-producing mutant of Serratia marcescens.

doi:10.1016/0168-1656(95)00103-9

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Article

Instability of the mutated biotin operon plasmid in a biotin-producing mutant of Serratia marcescens.

Journal of biotechnology - 21 Nov 1995

Sakurai N, Imai Y, Komatsubara S

Abstract excerpt

The growth of a d-biotin-producing strain of Serratia marcescens (SB412) was strongly inhibited by the introduction of pLGM412, a low-copy-number plasmid containing the complete biotin (bio) operon derived from SB412, whereas the wild-type strain was not inhibited by the plasmid. SB412 carrying p...

Topics

Bacterial Proteins
Biotin
Cell Division
Escherichia coli Proteins
Mutation
Operon
Plasmids
Rec A Recombinases
Restriction Mapping
Serratia marcescens
Sulfurtransferases
Transformation, Genetic

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