Article
[Correlation of E-cadherin polymorphisms to esophageal squamous cell carcinoma and gastric cardiac adenocarcinoma].
Ai zheng = Aizheng = Chinese journal of cancer - 1 May 2005
Zhang Xiu-Feng, Wang Yi-Min, Wang Rui, Wei Li-Zhen, Li Yan, Guo Wei, Wang Na, Zhang Jian-Hui
Abstract excerpt
BACKGROUND & OBJECTIVE: E-cadherin (CDH1) relates with invasion and metastasis of various cancers. Polymorphisms in the promoter region of E-cadherin gene may modify its transcriptional activity and protein level. This study was designed to investigate the correlation of CDH1 C-160A and G-347GA single nucleotide polymorphisms(SNPs) to susceptibilities and lymphatic metastases of esophageal squamous cell carcinoma...
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