Article
Association of a genetic polymorphism of the E-cadherin gene with prostate cancer in a Japanese population.
Japanese journal of clinical oncology - 1 Mar 2005
Kamoto Toshiyuki, Isogawa Yoshiaki, Shimizu Yousuke, Minamiguchi Sachiko, Kinoshita Hidefumi, Kakehi Yoshiyuki, Mitsumori Kenji, Yamamoto Shingo, Habuchi Tomonori, Kato Tetsuro, Ogawa Osamu
Abstract excerpt
The E-cadherin gene has been identified as having a physiological role in cellular attachment, and is hypothesized to participate in carcinogenesis. A polymorphism (an A to C substitution) in the 5'-untranslated region has a direct effect on E-cadherin gene transcriptional regulation. We explored...
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