Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Initiation and limitation of Ly-49A NK cell receptor acquisition by T cell factor-1.

Journal of immunology (Baltimore, Md. : 1950) - 15 Jul 2003

Ioannidis Vassilios, Kunz Béatrice, Tanamachi Dawn M, Scarpellino Léonardo, Held Werner

Abstract excerpt

The establishment of clonally variable expression of MHC class I-specific receptors by NK cells is not well understood. The Ly-49A receptor is used by approximately 20% of NK cells, whereby most cells express either the maternal or paternal allele and few express simultaneously both alleles. We have previously shown that NK cells expressing Ly-49A were reduced or almost absent in mice harboring a single or no...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Antigens, Ly
Share to Dose-Response Relationship, Immunologic

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Gene Rearrangement

Share to Hepatocyte Nuclear Factor 1-alpha

Share to Lectins, C-Type

Share to Lymphoid Enhancer-Binding Factor 1

Share to Mice, Inbred DBA

Share to Receptors, Immunologic

Source

Identifiers

PMID: 12847244
DOI: 10.4049/jimmunol.171.2.769

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Initiation and limitation of Ly-49A NK cell receptor acquisition by T cell factor-1.PMID 12847244Read ↗

An allele-specific, stochastic gene expression process controls the expression of multiple Ly49 family genes and generates a diverse, MHC-specific NK cell receptor repertoire.Semantic proximity Read ↗

Expression of the Ly49A gene in murine natural killer cell clones is predominantly but not exclusively mono-allelic.Semantic proximity Read ↗

Evidence for high bi-allelic expression of activating Ly49 receptors.Semantic proximity Read ↗

Allelic exclusion of Ly49-family genes encoding class I MHC-specific receptors on NK cells.Semantic proximity Read ↗

Activating Receptor Signals Drive Receptor Diversity in Developing Natural Killer Cells.Semantic proximity Read ↗

Expression of natural killer receptor alleles at different Ly49 loci occurs independently and is regulated by major histocompatibility complex class I molecules.Semantic proximity Read ↗

Effects of MHC class I alleles on licensing of Ly49A+ NK cells.Semantic proximity Read ↗

Mono-allelic Ly49 NK cell receptor expression.Semantic proximity Read ↗

Bidirectional promoters regulate the monoallelically expressed Ly49 NK receptors.Semantic proximity Read ↗

Genomic Ly49A transgenes: basis of variegated Ly49A gene expression and identification of a critical regulatory element.Semantic proximity Read ↗

Cloning of minimally divergent allelic forms of the natural killer (NK) receptor Ly-49C, differentially controlled by host genes in the MHC and NK gene complexes.Semantic proximity Read ↗

The NK2.1 receptor is encoded by Ly-49C and its expression is regulated by MHC class I alleles.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.