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Article

The role of ErbB2 signaling in the onset of terminal differentiation of oligodendrocytes in vivo.

The Journal of neuroscience : the official journal of the Society for Neuroscience - 2 Jul 2003

Kim Ju Young, Sun Qin, Oglesbee Michael, Yoon Sung Ok

Abstract excerpt

The knock-out analyses of neuregulin and its receptors have indicated that they play essential roles in Schwann cell development. However, the role they play in oligodendrocyte development in vivo has remained unclear, because such knock-out animals die before CNS myelination begins. We examined the role of neuregulin signaling in the CNS by generating transgenic mice that express a dominant-negative mutant of...

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Identifiers

PMID: 12843257
PMCID: PMC6741253

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MBP

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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