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Article

erbb3 and erbb2 are essential for schwann cell migration and myelination in zebrafish.

Current biology : CB - 29 Mar 2005

Lyons David A, Pogoda Hans-Martin, Voas Matthew G, Woods Ian G, Diamond Brianne, Nix Rebecca, Arana Naomi, Jacobs Jennifer, Talbot William S

Abstract excerpt

BACKGROUND: Myelin is critical for efficient axonal conduction in the vertebrate nervous system. Neuregulin (Nrg) ligands and their ErbB receptors are required for the development of Schwann cells, the glial cells that form myelin in the peripheral nervous system. Previous studies have not determined whether Nrg-ErbB signaling is essential in vivo for Schwann cell fate specification, proliferation, survival,...

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Identifiers

PMID: 15797019
DOI: 10.1016/j.cub.2005.02.030

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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