Article
Analysis of Pfmdr 1 gene in mefloquine-resistant Plasmodium falciparum.
Nucleic acids research. Supplement (2001) - 1 Jan 2001
Kim H S, Okuda Y, Begum K, Nagai Y, Wataya Y, Kimura M, Huruta T
Abstract excerpt
Drug resistance in Plasmodium falciparum is a serious problem in most endemic areas. Recent studies have suggested the potential involvement of genes in the MDR gene family in resistance to quinoline-containing compounds in P. falciparum. In our present studies, a molecular analysis of pfmdr 1 in isolate strain of P. falciparum, 523a R, from Japanese mefloquine-resistant patient was done to determine the reported...
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