Analysis of Pfmdr 1 gene in mefloquine-resistant Plasmodium falciparum.

doi:10.1093/nass/1.1.231

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Article

Analysis of Pfmdr 1 gene in mefloquine-resistant Plasmodium falciparum.

Nucleic acids research. Supplement (2001) - 1 Jan 2001

Kim H S, Okuda Y, Begum K, Nagai Y, Wataya Y, Kimura M, Huruta T

Abstract excerpt

Drug resistance in Plasmodium falciparum is a serious problem in most endemic areas. Recent studies have suggested the potential involvement of genes in the MDR gene family in resistance to quinoline-containing compounds in P. falciparum. In our present studies, a molecular analysis of pfmdr 1 in...

Topics

ATP-Binding Cassette Transporters
Alleles
Animals
Antimalarials
Drug Resistance
Genes, Protozoan
Humans
Mefloquine
Parasitic Sensitivity Tests
Plasmodium falciparum
Protozoan Proteins
RNA, Messenger
Reverse Transcriptase Polymerase Chain Reaction
Sequence Analysis, Protein

Source

Open in PubMed

Identifiers

PMID: 12836349
DOI: 10.1093/nass/1.1.231

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-12836349-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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