Stage-specific transcripts of the Plasmodium falciparum pfmdr 1 gene.

doi:10.1016/0166-6851(93)90196-5

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Article

Stage-specific transcripts of the Plasmodium falciparum pfmdr 1 gene.

Molecular and biochemical parasitology - 1 Feb 1993

Volkman S K, Wilson C M, Wirth D F

Abstract excerpt

Genes have been identified in Plasmodium falciparum which belong to the ATP-binding cassette superfamily of transport systems based upon sequence and structural homology. One of these genes, the pfmdr 1 gene, is homologous to the mammalian mdr 1 gene, which encodes the P-glycoprotein product. Str...

Topics

Animals
Drug Resistance
Gene Expression
Genes, Protozoan
Mefloquine
Phenotype
Plasmodium falciparum
Poly A
RNA, Messenger
RNA, Protozoan
Transcription, Genetic

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