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Article

The effect of acetate pathway mutations on the production of pyruvate in Escherichia coli.

Applied microbiology and biotechnology - 1 Jul 2003

Tomar A, Eiteman M A, Altman E

Abstract excerpt

We compared pyruvate accumulation in six strains of Escherichia coli and their corresponding ppc mutants. Each strain contained a mutation of a gene involved in the pathway to acetate synthesis. Strains with mutations in genes encoding the pyruvate dehydrogenase complex generally exhibited the greatest pyruvate accumulation of which CGSC6162 (an aceF mutant) and CGSC6162 Delta ppc were studied in greater detail...

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Identifiers

PMID: 12835924
DOI: 10.1007/s00253-003-1234-6

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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