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Article

zag-1, a Zn-finger homeodomain transcription factor controlling neuronal differentiation and axon outgrowth in C. elegans.

Development (Cambridge, England) - 1 Aug 2003

Wacker Irene, Schwarz Valentin, Hedgecock Edward M, Hutter Harald

Abstract excerpt

The nervous system consists of diverse subtypes of neurons, whose identities must be specified during development. One important aspect of the differentiation program of neurons is the expression of the appropriate set of genes controlling axon pathway selection. We have identified a novel Znfinger/homeodomain containing transcription factor, zag-1, required for particular aspects of axonal pathfinding. In zag-1...

Topics

Amino Acid Sequence
Animals
Axons
Caenorhabditis elegans
Caenorhabditis elegans Proteins
Cell Differentiation
Cell Movement
Cloning, Molecular
Genes, Reporter
Homeodomain Proteins

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Humans

Mesoderm

Molecular Sequence Data

Mutation

Nerve Tissue Proteins

Neurons

Neurotransmitter Agents

Organisms, Genetically Modified

Source

Identifiers

PMID: 12835395
DOI: 10.1242/dev.00570

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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