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Article

Shootin-1 is required for nervous system development in zebrafish.

Developmental dynamics : an official publication of the American Association of Anatomists - 1 Oct 2020

Emerson Sarah E, Stergas Helaina R, Bupp-Chickering Simon O, Ebert Alicia M

Abstract excerpt

BACKGROUND: Semaphorin6A (Sema6A) and its PlexinA2 (PlxnA2) receptor canonically function as repulsive axon guidance cues. To understand downstream signaling mechanisms, we performed a microarray screen and identified the "clutch molecule" shootin-1 (shtn-1) as a transcriptionally repressed target. Shtn-1 is a key proponent of cell migration and neuronal polarization and must be regulated during nervous system...

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PMID: 32406957
DOI: 10.1002/dvdy.194

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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